The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Feb. 18, 2010
Applicants:
Laura J Chambers, Harlow, GB;
Robert Gleave, Harlow, GB;
Stefan Senger, Stevenage, GB;
Daryl Simon Walter, Harlow, GB;
Inventors:
Laura J Chambers, Harlow, GB;
Robert Gleave, Harlow, GB;
Stefan Senger, Stevenage, GB;
Daryl Simon Walter, Harlow, GB;
Assignee:
Glaxo Group Limited, Greenford, Middlesex, GB;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4015 (2006.01); C07D 207/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.