The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2011

Filed:

Aug. 01, 2008
Applicants:

Naoya Ono, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Tetsuya Yabuuchi, Toshima-ku, JP;

Hironori Katakai, Toshima-ku, JP;

Inventors:

Naoya Ono, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Tetsuya Yabuuchi, Toshima-ku, JP;

Hironori Katakai, Toshima-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 413/12 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 213/70 (2006.01); C07D 213/68 (2006.01); C07D 213/643 (2006.01); A61K 31/5377 (2006.01); A61K 31/496 (2006.01); A61K 31/4725 (2006.01); A61K 31/4709 (2006.01); A61K 31/4439 (2006.01); A61K 31/4436 (2006.01); A61K 31/443 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound represented by formula (I) or a pharmaceutically acceptable salt thereof: (wherein Yrepresents a nitrogen atom or a group represented by CR, Yrepresents a nitrogen atom or a group represented by CR, Yrepresents a nitrogen atom or a group represented by CR, R, Rand R, which may be the same or different, each represent a hydrogen atom, etc. (excluding the case where Yis CR, Yis CRand Yis CR), X represents an oxygen atom, etc., Rrepresents a C-Calkyl group, etc., Rrepresents a C-Calkyl group, etc., Rrepresents an optionally substituted phenyl group, etc., Rrepresents a hydrogen atom, etc., and Rrepresents an optionally substituted phenyl group, etc.) has an inhibitory effect on the binding between S1P and its receptor Edg-1(S1P), and is useful as a therapeutic agent for autoimmune diseases, rheumatoid arthritis, asthma, atopic dermatitis, rejection after organ transplantation, cancer, retinopathy, psoriasis, osteoarthritis, or age-related macular degeneration, etc.


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