The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Jun. 06, 2003
Applicants:
Henry C. Lai, Seattle, WA (US);
Tomikazu Sasaki, Bothell, WA (US);
Narendra P. Singh, Lynnwood, WA (US);
Inventors:
Henry C. Lai, Seattle, WA (US);
Tomikazu Sasaki, Bothell, WA (US);
Narendra P. Singh, Lynnwood, WA (US);
Assignee:
University of Washington, Seattle, WA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 47/00 (2006.01); A61K 43/00 (2006.01); A61K 35/00 (2006.01); C07D 323/00 (2006.01); A01N 43/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
In one aspect, the invention provides covalent conjugates between artemisinin-related endoperoxides and iron-carrying proteins. In some embodiments, the covalent conjugates comprise artelinate and holotransferrin. In another aspect, the invention provides methods for administering the covalent conjugates of the invention to treat cancer and infections by pathogens that bind iron-carrying proteins.