The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Dec. 11, 2009
Masakazu Sugiyama, Kanagawa, JP;
Kunihiko Watanabe, Kanagawa, JP;
Kenichi Mori, Kanagawa, JP;
Hiroyuki Nozaki, Kanagawa, JP;
Masakazu Sugiyama, Kanagawa, JP;
Kunihiko Watanabe, Kanagawa, JP;
Kenichi Mori, Kanagawa, JP;
Hiroyuki Nozaki, Kanagawa, JP;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).