The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2011
Filed:
Jan. 16, 2009
Tsai-yueh Luo, Longtan Township, Taoyuan County, TW;
I-chung Tang, Pingjhen, TW;
Show-wen Liu, Shetou Township, Changhua County, TW;
Yu-lung Wu, Bade, TW;
Cheng-hsien Lin, Taipei, TW;
Cheng-fang Hsu, Toufen Township, Miaoli County, TW;
Kwei-luen Hsu, Hsinchu, TW;
Chang-mau Sheng, Taipei, TW;
Ching-jun Liou, Longtan Township, Taoyuan County, TW;
Te-sheng Liang, Taipei, TW;
Tsai-Yueh Luo, Longtan Township, Taoyuan County, TW;
I-Chung Tang, Pingjhen, TW;
Show-Wen Liu, Shetou Township, Changhua County, TW;
Yu-Lung Wu, Bade, TW;
Cheng-Hsien Lin, Taipei, TW;
Cheng-Fang Hsu, Toufen Township, Miaoli County, TW;
Kwei-Luen Hsu, Hsinchu, TW;
Chang-Mau Sheng, Taipei, TW;
Ching-Jun Liou, Longtan Township, Taoyuan County, TW;
Te-Sheng Liang, Taipei, TW;
Atomic Energy Council-Institute of Nuclear Energy Research, Taoyuan County, TW;
Abstract
A radioactive mixture and a manufacturing method thereof are disclosed. The radioactive mixture (Re-MN/Lipiodol mixture) is formed by chelating reaction of MN series compounds that are amine-amide-disulfide amine quadric-dentate chelate ligands with TcO/or ReO, and then dissolved in Lipiodol. Moreover, theTc/orRe of the TcO/or ReOavoids bone marrow injuries caused by freeY. By the feature of the Lipiodol that stays in liver tumors for a long period, the radioactive mixture is applied to treat liver cancers by injection so that injuries caused by surgical operations can be prevented.Re-MN/Lipiodol is used for liver cancer, breast cancer or other solid tumors treatment. Re-188 MN or Re-188 MN/Lipiodol can be mixed with anticancer drugs, hydrogel, liposome, micelle or other nano-particles to form the multifunctional therapeutic modality.