The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2011
Filed:
Jul. 16, 2007
Applicants:
Nuria Busquets Baque, Barcelona, ES;
Francesca Pajuelo Lorenzo, El Prat de Llobregat, ES;
Inventors:
Nuria Busquets Baque, Barcelona, ES;
Francesca Pajuelo Lorenzo, El Prat de Llobregat, ES;
Assignee:
Laboratorios Almirall, S.A., Barcelona, ES;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 453/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
This present disclosure relates to a process for manufacturing 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide by reacting 2-hydroxy-2,2-dithien-2-ylacetic acid 1-azabicyclo[2.2.2]oct-3(R)yl ester and 3-phenoxypropyl bromide, wherein the reaction takes place in a solvent or mixtures of solvents having a boiling point from 50° C. to 210° C. and chosen from ketones and cyclic ethers.