The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2011

Filed:

May. 09, 2008
Applicants:

Michael George Thomas, Madison, WI (US);

Elizabeth Anne Felnagle, Madison, WI (US);

Michelle Renee Rondon, Madison, WI (US);

Andrew David Berti, Madison, WI (US);

Inventors:

Michael George Thomas, Madison, WI (US);

Elizabeth Anne Felnagle, Madison, WI (US);

Michelle Renee Rondon, Madison, WI (US);

Andrew David Berti, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12P 19/62 (2006.01); C12N 1/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are nucleic acid molecules comprising at least a functional fragment of the capreomycin biosynthetic gene cluster, polypeptides encoded by the cluster and recombinant host cells transformed with any of the nucleic acid molecules disclosed herein. Various methods using any of the vectors or expression cassettes that encode one or more of the gene products of the cluster are provided for heterologous production of capreomycin and capreomycin derivatives.


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