The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2011
Filed:
Sep. 06, 2006
Peter Kwong, Washington, DC (US);
John Mascola, Rockville, MD (US);
Gary Nabel, Washington, DC (US);
Richard Wyatt, Rockville, MD (US);
Barna Dey, Germantown, MD (US);
Ling Xu, Potomac, MD (US);
Tongqing Zhou, Boyds, MD (US);
Chih-chin Huang, Sylvania, OH (US);
Joseph Sodroski, Boston, MA (US);
Wen Yuan, Brighton, MA (US);
Shi-hua Xiang, Boston, MA (US);
Peter Kwong, Washington, DC (US);
John Mascola, Rockville, MD (US);
Gary Nabel, Washington, DC (US);
Richard Wyatt, Rockville, MD (US);
Barna Dey, Germantown, MD (US);
Ling Xu, Potomac, MD (US);
Tongqing Zhou, Boyds, MD (US);
Chih-Chin Huang, Sylvania, OH (US);
Joseph Sodroski, Boston, MA (US);
Wen Yuan, Brighton, MA (US);
Shi-Hua Xiang, Boston, MA (US);
The United States of America as represented by the Secretary of the Department of Health and Human Services, Washington, DC (US);
Dana Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed.