The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2011

Filed:

Aug. 19, 2008
Applicants:

Akiko Hisada, Kawagoe, JP;

Ryosuke Takahashi, Kawagoe, JP;

Hiroko Hanzawa, Tokorozawa, JP;

Inventors:

Akiko Hisada, Kawagoe, JP;

Ryosuke Takahashi, Kawagoe, JP;

Hiroko Hanzawa, Tokorozawa, JP;

Assignee:

Hitachi, Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/12 (2006.01); C12N 5/00 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a monoclonal antibody displaying excellent specificity against heparan sulfate saccharide chains for the analysis of heparan sulfate saccharide chains specific to dentin. The invention also provides a method of evaluating reproductive dentin using the monoclonal antibody. The anti-heparan sulfate monoclonal antibody reacts against dentin-derived heparan sulfate and in particular the anti-heparan sulfate monoclonal antibody reacts strongly and specifically with uncalcified predentin regions. In the method of evaluating dentin, the antibody is reacted against an isolated dentin-derived sample and the reaction is used in order to evaluate the development of dentin.


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