The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2011
Filed:
Nov. 22, 2008
Applicants:
Jeanne Y. Wei, Little Rock, AR (US);
Gohar Azhar, Little Rock, AR (US);
Xiaomin Zhang, Little Rock, AR (US);
Inventors:
Jeanne Y. Wei, Little Rock, AR (US);
Gohar Azhar, Little Rock, AR (US);
Xiaomin Zhang, Little Rock, AR (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12Q 1/68 (2006.01); A61K 48/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a method of identifying candidate agents to test for treating heart failure involving diastolic impairment, the method comprising: testing an agent to determine whether it (a) binds to serum response factor (SRF), (b) reduces SRF binding to a serum response element (SRE), or (c) reduces SRF protein levels in a cell; wherein if the agent does one or more of (a), (b), and (c), it is identified as a candidate agent.