The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2011

Filed:

Dec. 28, 2007
Applicants:

Kazuyoshi Aso, Osaka, JP;

Michiyo Mochizuki, Osaka, JP;

Katsumi Kobayashi, Osaka, JP;

Inventors:

Kazuyoshi Aso, Osaka, JP;

Michiyo Mochizuki, Osaka, JP;

Katsumi Kobayashi, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); C07D 235/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided a compound of the formula: wherein Ris an optionally substituted hydrocarbyl, a substituted amino, etc.; Ris an aromatic group substituted with one or two substituents at the positions adjacent to the position bonded to Z, and said aromatic group may have additional substituent(s); X is —NR— wherein Ris a hydrogen, an optionally substituted hydrocarbyl or an acyl, or sulfur; Y, Yand Yare an optionally substituted methine or a nitrogen, etc.; and Z is an optionally substituted methylene, provided that carbonyl is excluded; or a salt thereof or a prodrug thereof, which have CRF receptor antagonist activity and use thereof.


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