The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2011

Filed:

Oct. 26, 2007
Applicants:

Min GE, Edison, NJ (US);

Songnian Lin, Monroe, NJ (US);

Shawn P. Walsh, Bridgewater, NJ (US);

Lihu Yang, Edison, NJ (US);

Changyou Zhou, Princeton, NJ (US);

Inventors:

Min Ge, Edison, NJ (US);

Songnian Lin, Monroe, NJ (US);

Shawn P. Walsh, Bridgewater, NJ (US);

Lihu Yang, Edison, NJ (US);

Changyou Zhou, Princeton, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/192 (2006.01); A61K 31/277 (2006.01); C07D 487/02 (2006.01); C07D 217/24 (2006.01); C07D 213/36 (2006.01); C07D 209/34 (2006.01); C07D 311/34 (2006.01); C07D 333/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

Diaryl ethers in which one of the aryl groups is a phenyl fused to a cycloalkyl or heterocyclic ring, to which is attached an acetic acid group, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that often accompany this disease, including insulin resistance, obesity and lipid disorders.


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