The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2011

Filed:

Jul. 22, 2010
Applicants:

Andre Bubendorf, Uffheim, FR;

Annette Deynet-vucenovic, Loerrach, DE;

Ralph Diodone, Breisach, DE;

Olaf Grassmann, Loerrach, DE;

Kai Lindenstruth, Loerrach, DE;

Emmanuel Pinard, Linsdorf, FR;

Franziska E. Rohrer, Riehen, CH;

Urs Schwitter, Reinach BL, CH;

Inventors:

Andre Bubendorf, Uffheim, FR;

Annette Deynet-Vucenovic, Loerrach, DE;

Ralph Diodone, Breisach, DE;

Olaf Grassmann, Loerrach, DE;

Kai Lindenstruth, Loerrach, DE;

Emmanuel Pinard, Linsdorf, FR;

Franziska E. Rohrer, Riehen, CH;

Urs Schwitter, Reinach BL, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 213/74 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to four distinct crystalline forms and to an amorphous form of [4-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-[5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-methanone, and to their use in the preparation of pharmaceutical compositions. The compounds of present invention are suitable for the treatment of psychoses, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other diseases in which cognitive processes are impaired, such as attention deficit disorders or Alzheimer's disease.


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