The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2011

Filed:

Aug. 29, 2008
Applicants:

Gérard Coquerel, Notre Dame de Bondeville, FR;

Guillaume Tauvel, Rouen, FR;

Marie-noelle Petit, Mont Saint Aignan, FR;

Inventors:

Gérard Coquerel, Notre Dame de Bondeville, FR;

Guillaume Tauvel, Rouen, FR;

Marie-Noelle Petit, Mont Saint Aignan, FR;

Assignee:

Universite de Rouen, Mont-Saint-Aignan, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the resolution by preferential crystallization of potassium salts of racemic omeprazole which is a solvate of ethanol and/or of ethylene glycol, which consists in converting the omeprazole to the potassium salt in the form of a solvate or of a mixture of these solvates in the presence of an excess of inorganic base which is a source of potassium, the said potassium salts existing in the form of conglomerates, and in then resolving the said conglomerates, independently or simultaneously, by preferential crystallization in order to separate the two (S) and (R) enantiomers of these potassium salts of omeprazole.


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