The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2011

Filed:

Aug. 08, 2007
Applicants:

David S. Weinstein, East Windsor, NJ (US);

Ping Chen, Belle Mead, NJ (US);

T. G. Murali Dhar, Newtown, PA (US);

Jingwu Duan, Yardley, PA (US);

Hua Gong, King of Prussia, PA (US);

Bin Jiang, Norristown, PA (US);

Bingwei Vera Yang, Belle Mead, NJ (US);

Arthur M. Doweyko, Long Valley, NJ (US);

Inventors:

David S. Weinstein, East Windsor, NJ (US);

Ping Chen, Belle Mead, NJ (US);

T. G. Murali Dhar, Newtown, PA (US);

Jingwu Duan, Yardley, PA (US);

Hua Gong, King of Prussia, PA (US);

Bin Jiang, Norristown, PA (US);

Bingwei Vera Yang, Belle Mead, NJ (US);

Arthur M. Doweyko, Long Valley, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); A61K 31/436 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including inflammatory and immune diseases, having the structure of formula (I): an enantiomer, diastereomer, or tautomer thereof, or a prodrug ester thereof, or a pharmaceutically-acceptable salt thereof, in which: Also provided are pharmaceutical compositions and methods of treating inflammatory- or immune-associated diseases and obesity and diabetes employing said compounds.


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