The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2011
Filed:
Aug. 31, 2006
Pavel Hradil, Hlusovice, CZ;
Lubomir Kvapil, Slatinice, CZ;
Roman Gabriel, Olomouc, CZ;
Martin Grepl, Hlusovice, CZ;
Jan Novotny, Olomouc, CZ;
Petr Slezar, Olomouc, CZ;
Radek Melnicky, Sternberk, CZ;
Pavel Hradil, Hlusovice, CZ;
Lubomir Kvapil, Slatinice, CZ;
Roman Gabriel, Olomouc, CZ;
Martin Grepl, Hlusovice, CZ;
Jan Novotny, Olomouc, CZ;
Petr Slezar, Olomouc, CZ;
Radek Melnicky, Sternberk, CZ;
Farmak, A.S., Olomouc, CZ;
Abstract
A method for the preparation of salts of 2-[2-(4-dibenzo[b,fj[1,4]thiazepin-11-yl-1 -piperazinyl)ethoxy]ethanol (quetiapine) from the quetiapine base and the respective acid, wherein the salt is precipitated from a mixture of solvents, the mixture being either a mixture of an aromatic hydrocarbon and a ketone or ester, or that of an aromatic hydrocarbon, water and a ketone or ester. The salts of quetiapine are purified by partial crystallization, wherein only a part of the salt of quetiapine is dissolved in a Cto Calcohol used.