The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2011
Filed:
Oct. 06, 2006
Applicants:
Sean Whelan, Cambridge, MA (US);
Jianrong LI, Columbus, OH (US);
Inventors:
Sean Whelan, Cambridge, MA (US);
Jianrong Li, Columbus, OH (US);
Assignee:
Presidents and Fellows of Harvard College, Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/205 (2006.01); A61K 39/12 (2006.01); C12N 7/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to an attenuated non-segmented negative-sense RNA virus characterized by at least one mutation in the L gene wherein the mutation reduces viral replication, the methods of manufacturing and methods of use.