The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2011
Filed:
Feb. 24, 2010
Michel Morre, Boulogne, FR;
Brigitte Assouline, Courbevoie, FR;
Iann Rance, Sevres, FR;
Anne Gregoire, Auzecort, FR;
Corinne Breque, Vanves, FR;
Michel Morre, Boulogne, FR;
Brigitte Assouline, Courbevoie, FR;
Iann Rance, Sevres, FR;
Anne Gregoire, Auzecort, FR;
Corinne Breque, Vanves, FR;
Cytheris, Issy les Moulineaux, FR;
Abstract
The present invention relates to new and improved interleukin-7 polypeptides, as well as compositions comprising the same, their preparation and uses. The invention more particularly relates to hyperglycosylated IL-7 polypeptides having improved properties, as well as their manufacture and therapeutic uses. The invention also discloses novel IL-7 polypeptides having modified amino acid sequences containing artificially created glycosylation site(s), as well as corresponding nucleic acid molecules, vectors and recombinant host cells. The invention also relates to the use of such polypeptides, cells or nucleic acids for curative or preventive treatment of mammalian subjects, including human subjects.