The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2011
Filed:
Feb. 17, 2005
Varda Shoshan-bar-matz, Omer, IL;
Adrian Israelson, Beer Sheva, IL;
Varda Shoshan-Bar-Matz, Omer, IL;
Adrian Israelson, Beer Sheva, IL;
The National Institute for Biotechnology in the Negev Ltd., Beer Sheva, IL;
Abstract
The present invention provides a photoreactive reagent that binds specifically to Ca-binding proteins, links to them covalently after photo-activation, and labels them. The novel reagent enables the characterization, purification, inhibition and screening of Ca-binding proteins, as well as the preparation of a new affinity chromatography matrix and a new protein biosensor. The invention also relates to the use of the reagent in inhibiting apoptosis and necrosis and in diagnosing a disorder associated with a defect in the function of a Ca-binding protein, and in the preparation of a medicament for treating such disorders.