The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2011
Filed:
Jun. 22, 2009
Jacob Matthew Hooker, Port Jefferson, NY (US);
Matthias Schonberger, Mains, DE;
Hanno Schieferstein, Aabergen, DE;
Joanna S. Fowler, Bellport, NY (US);
Jacob Matthew Hooker, Port Jefferson, NY (US);
Matthias Schonberger, Mains, DE;
Hanno Schieferstein, Aabergen, DE;
Joanna S. Fowler, Bellport, NY (US);
Brookhaven Science Associates, LLC, Upton, NY (US);
Abstract
Isotopically labeled formaldehyde (*CHO) is prepared from labeled methyl iodide (*CHI) by reaction with an oxygen nucleophile having a pendant leaving group. The mild and efficient reaction conditions result in good yields of *CHO with little or no *C isotopic dilution. The simple, efficient production ofCHO is described. The use of theCHO for the formation of positron emission tomography tracer compounds is described. The reaction can be incorporated into automated equipment available to radiochemistry laboratories. The isotopically labeled formaldehyde can be used in a variety of reactions to provide radiotracer compounds for imaging studies as well as for scintillation counting and autoradiography.