The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2011
Filed:
Jan. 11, 2008
Applicants:
Robert Bittman, Roslyn Heights, NY (US);
Zaiguo LI, Fresh Meadows, NY (US);
Inventors:
Robert Bittman, Roslyn Heights, NY (US);
Zaiguo Li, Fresh Meadows, NY (US);
Assignee:
Research Foundation of the City University of New York, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to free cholesterol analogs bearing a boron dipyrromethene difluoro (BODIPY) fluorophore in the side chain and methods of preparation. The compounds of the present invention can be used in fluorescence spectroscopy and fluorescence microscopy to visualize the exchange, distribution, and trafficking of free cholesterol between living cells and to monitor the movement of free cholesterol between ordered and disordered lipid domains in membranes.