The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2011

Filed:

Jun. 09, 2004
Applicants:

Alan P. Kozikowski, Chicago, IL (US);

John L. Musachio, Baltimore, MD (US);

Kenneth J. Kellar, Bethesda, MD (US);

Yingxian Xiao, Potomac, MD (US);

Zhi-liang Wei, Chicago, IL (US);

Hong Fan, Timonium, MD (US);

Inventors:

Alan P. Kozikowski, Chicago, IL (US);

John L. Musachio, Baltimore, MD (US);

Kenneth J. Kellar, Bethesda, MD (US);

Yingxian Xiao, Potomac, MD (US);

Zhi-Liang Wei, Chicago, IL (US);

Hong Fan, Timonium, MD (US);

Assignees:

Georgetown University, Washington, DC (US);

The John Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4427 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

One aspect of the present invention relates to heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. A second aspect of the invention relates to the use of a compound of the invention for modulation of a mammalian nicotinic acetylcholine receptor. The present invention also relates to the use of a compound of the invention for treating a mammal suffering from Alzheimer's disease, Parkinson's disease, dyskinesias, Tourette's syndrome, schizophrenia, attention deficit disorder, anxiety, pain, depression, obsessive compulsive disorder, chemical substance abuse, alcoholism, memory deficit, pseudodementia, Ganser's syndrome, migraine pain, bulimia, obesity, premenstrual syndrome or late luteal phase syndrome, tobacco abuse, post-traumatic syndrome, social phobia, chronic fatigue syndrome, premature ejaculation, erectile difficulty, anorexia nervosa, disorders of sleep, autism, mutism or trichtillomania.


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