The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2011
Filed:
May. 26, 2006
Josef Messinger, Sehnde, DE;
Heinrich-hubert Thole, Hannover, DE;
Bettina Husen, Hannover, DE;
Michael Weske, Burgdorf, DE;
Pasi Koskimies, Turku, FI;
Lila Pirkkala, Kaarina, FI;
Josef Messinger, Sehnde, DE;
Heinrich-Hubert Thole, Hannover, DE;
Bettina Husen, Hannover, DE;
Michael Weske, Burgdorf, DE;
Pasi Koskimies, Turku, FI;
Lila Pirkkala, Kaarina, FI;
Abbott Products GmbH, Hannover, DE;
Abstract
The present invention relates to novel substituted steroid derivatives which represent selective inhibitors of the 17β-hydroxysteroid dehydrogenase type I (17β-HSD1) and, in addition, which may represent inhibitors of the steroid sulphatase, as well as to their salts, to pharmaceutical preparations containing these compounds and to processes for the preparation of these compounds. Furthermore, the invention concerns the therapeutic use of said novel substituted steroid derivatives, particularly their use in the treatment, inhibition, prophylaxis or prevention of steroid hormone dependent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of 17β-hydroxysteroid dehydrogenase type I and/or steroid sulphatase enzymes and/or requiring the lowering of the endogenous 17β-estradiol concentration.