The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2011

Filed:

Mar. 03, 2006
Applicants:

Barry Victor Lloyd Potter, The Oxford Science Park, GB;

Michael John Reed, The Oxford Science Parl, GB;

Lok Wai Lawrence Woo, The Oxford Science Park, GB;

Hatem Hejaz, Dubai, AE;

Bertrand Leblond, The Oxford Science Park, GB;

Matthew Paul Leese, The Oxford Science Park, GB;

Atul Purohit, Oxford, GB;

Inventors:

Barry Victor Lloyd Potter, The Oxford Science Park, GB;

Michael John Reed, The Oxford Science Parl, GB;

Lok Wai Lawrence Woo, The Oxford Science Park, GB;

Hatem Hejaz, Dubai, AE;

Bertrand Leblond, The Oxford Science Park, GB;

Matthew Paul Leese, The Oxford Science Park, GB;

Atul Purohit, Oxford, GB;

Assignee:

Sterix Limited, Slough Berkshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); C07J 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided a compound of Formula I wherein X is a ring system; Ris any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; Ris any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein when X is a steroidal structure and both of Rand Rare sulphamate groups, the steroidal ring system (X) represents an oestrogen; and wherein said compound is capable of inhibiting steroid sulphatase (STS) activity and/or is capable of acting as a modulator of cell cycling and/or as a modulator of apoptosis and/or as a modulator of cell growth. There is also provided a compound of Formula VIII wherein Ris any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; and wherein said compound is capable of inhibiting steroid sulphatase (STS) activity and/or is capable of acting as a modulator of cell cycling and/or as a modulator of apoptosis and/or as a modulator of cell growth.


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