The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2011
Filed:
Dec. 30, 2003
Sang Yup Lee, Daejeon, KR;
Tae Jung Park, Daejeon, KR;
Jong Pil Park, Yongin, KR;
Seok Jae Lee, Daejeon, KR;
Jae-gu Pan, Chungcheongnamdo, KR;
Heung-chae Jung, Deajeon, KR;
Soo-keun Choi, Deajeon, KR;
Sang Yup Lee, Daejeon, KR;
Tae Jung Park, Daejeon, KR;
Jong Pil Park, Yongin, KR;
Seok Jae Lee, Daejeon, KR;
Jae-Gu Pan, Chungcheongnamdo, KR;
Heung-Chae Jung, Deajeon, KR;
Soo-Keun Choi, Deajeon, KR;
Korea Advanced Institute of Science and Technology, Daejeon, KR;
Genofocus, Inc., Daejeon, KR;
Abstract
The present invention relates to a method for expressing a target protein on an exosporium forming the outermost surface of bacterial spores. More particularly, the present invention relates to a method for expressing a target protein on the surface of cells and spores using an exosporium as a matrix for surface expression, and methods for the production of a protein array, the production of antibodies, the separation of a certain substance from a mixture, bioconversion, and the improvement of a target protein, which are characterized by using the cells or spores having the target protein that was expressed on the surface by the above expression method. The method for expressing the target protein on the surface of the spore outer membrane of the gene carriers according to the present invention has effects in that a variety of the target proteins can be expressed and the level of surface expression of the target protein is increased compared to the existing technology, and also the structural stability of the gene carriers having the target protein expressed on their surface, the viability of the host, and the rapidity of the screening method, are greatly increased.