The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2011

Filed:

Mar. 30, 2010
Applicants:

Sapna S. Shah, Jamesburg, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Xianhai Huang, Warren, NJ (US);

Dong Xiao, Warren, NJ (US);

Sunil Paliwal, Monroe Township, NJ (US);

Hon-chung Tsui, East Brunswick, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Ashwin U. Rao, Avenel, NJ (US);

Cheng Wang, King of Prussia, PA (US);

Neng-yang Shih, Warren, NJ (US);

Inventors:

Sapna S. Shah, Jamesburg, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Xianhai Huang, Warren, NJ (US);

Dong Xiao, Warren, NJ (US);

Sunil Paliwal, Monroe Township, NJ (US);

Hon-Chung Tsui, East Brunswick, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Ashwin U. Rao, Avenel, NJ (US);

Cheng Wang, King of Prussia, PA (US);

Neng-Yang Shih, Warren, NJ (US);

Assignee:

OPKO Health, Inc., Miami, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/02 (2006.01); C07D 215/12 (2006.01); C07D 215/16 (2006.01); C07D 213/02 (2006.01); C07D 211/02 (2006.01); C07D 405/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound having the general structure shown in Formula I: or pharmaceutically acceptable salt and/or solvates thereof are useful in treating diseases or conditions mediated by NKreceptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.


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