The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2011

Filed:

Apr. 12, 2007
Applicants:

Anna-karin Tiden, Sodertalje, SE;

Jenny Viklund, Sodertalje, SE;

Inventors:

Anna-Karin Tiden, Sodertalje, SE;

Jenny Viklund, Sodertalje, SE;

Assignee:

AstraZeneca AB, Södertälje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/22 (2006.01); A61K 31/522 (2006.01); A61P 9/10 (2006.01); A61P 11/00 (2006.01); A61P 11/08 (2006.01); A61P 25/16 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are disclosed novel compounds of Formula (I) wherein L, R, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme MPO and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders, cardio- and cerebrovascular atherosclerotic disorders and peripheral artery disease and respiratory disorders.


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