The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2011
Filed:
Sep. 11, 2008
Marlon D. Cowart, Round Lake Beach, IL (US);
Kennan C. Marsh, Lake Forest, IL (US);
Huaqing Liu, Buffalo Grove, IL (US);
Jae Y. Lee, Buffalo Grove, IL (US);
Maria G. Beconi, Lake Forest, IL (US);
Jill M. Wetter, Beach Park, IL (US);
Lawrence A. Black, Libertyville, IL (US);
Thomas C. Custer, Lake Bluff, IL (US);
Marlon D. Cowart, Round Lake Beach, IL (US);
Kennan C. Marsh, Lake Forest, IL (US);
Huaqing Liu, Buffalo Grove, IL (US);
Jae Y. Lee, Buffalo Grove, IL (US);
Maria G. Beconi, Lake Forest, IL (US);
Jill M. Wetter, Beach Park, IL (US);
Lawrence A. Black, Libertyville, IL (US);
Thomas C. Custer, Lake Bluff, IL (US);
Abbott Laboratories, Abbott Park, IL (US);
Abstract
The invention relates to octahydro-pyrrolo[3,4-b]pyrrole N-oxides as prodrugs of CNS-active compounds, compositions comprising such compounds, methods for making the compounds, salts, and polymorphs, and methods of treating conditions and disorders using such compounds and compositions. Octahydro-pyrrolo[3,4-b]pyrrole N-oxides of formula (I) are prodrugs of histamine-3 antagonists, and are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole N-oxide compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.