The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2011
Filed:
May. 23, 2002
Herman Jan Tijmen Coelingh Bennink, Driebergen, NL;
Evert Johannes Bunschoten, Heesch, NL;
Christian Franz Holinka, New York, NY (US);
Herman Jan Tijmen Coelingh Bennink, Driebergen, NL;
Evert Johannes Bunschoten, Heesch, NL;
Christian Franz Holinka, New York, NY (US);
Pantarhei Bioscience B.V., , NL;
Abstract
One aspect of the present invention relates to a method of hormone replacement in mammals, which method comprises the oral administration of an estrogenic component and a progestogenic component to a mammal in an effective amount to prevent or treat symptoms of hypoestrogenism, wherein the estrogenic component is selected from the group consisting of substances represented by the above formula in which formula R, R, R, Rindependently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R, R, Ris a hydroxyl group; and no more than 3 of R, R, R, Rare hydrogen atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors. Another aspect of the invention concerns a pharmaceutical kit comprising oral dosage units that contain the aforementioned estrogenic component and a progestogenic component as well as an androgenic component.