The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2011
Filed:
Mar. 24, 2008
Fariba Masoumeh Assadi-porter, Fitchburg, WI (US);
Mark E. Cook, Madison, WI (US);
Hamid Reza Eghbalnia, Madison, WI (US);
Marco Tonelli, Madison, WI (US);
Warren Paul Porter, Fitchburg, WI (US);
Daniel Elmer Butz, Madison, WI (US);
Fariba Masoumeh Assadi-Porter, Fitchburg, WI (US);
Mark E. Cook, Madison, WI (US);
Hamid Reza Eghbalnia, Madison, WI (US);
Marco Tonelli, Madison, WI (US);
Warren Paul Porter, Fitchburg, WI (US);
Daniel Elmer Butz, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
The invention is methods and related kits for diagnosing a disease state of cachexia by measuring biomarker profiles from a biological sample. Rapid measurement of early onset or progression of the disease in a subject is determined by measuring biomarker levels from the subject and optionally comparing the biomarker levels to a standard biomarker profile or metabolome phase portrait for the disease. The biomarkers measured in the assay and related kit for cachexia progression include biomarkers selected from the group consisting of lactate, citrate, formate, acetoacetate, 3-hydroxy butrate, alanine, glutamine, glutamate, valine, isoleucine leucine, thrionine, lysine, arginine, tyrosine, phenyl alanine, histidine and tryptophan.