The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2011

Filed:

Aug. 15, 2006
Applicants:

Kari Alitalo, Helsinki, FI;

Tuomas Tammela, Helsinki, FI;

Salla Keskitalo, Helsinki, FI;

Katri Pajusola, Helsinki, FI;

Markku M. Jeltsch, Helsinki, FI;

Seppo Yla-herttuala, Helsinki, FI;

Terhi Karpanen, Helsinki, FI;

Ulf Eriksson, Stockholm, SE;

Marko J. T. Uutela, Helsinki, FI;

Inventors:

Kari Alitalo, Helsinki, FI;

Tuomas Tammela, Helsinki, FI;

Salla Keskitalo, Helsinki, FI;

Katri Pajusola, Helsinki, FI;

Markku M. Jeltsch, Helsinki, FI;

Seppo Yla-Herttuala, Helsinki, FI;

Terhi Karpanen, Helsinki, FI;

Ulf Eriksson, Stockholm, SE;

Marko J. T. Uutela, Helsinki, FI;

Assignee:

Vegenics Pty Ltd, Toorak, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 39/00 (2006.01); A61K 38/24 (2006.01); A61F 13/00 (2006.01); A61B 17/10 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.


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