The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2011
Filed:
Nov. 07, 2006
Fukushi Hirayama, Tokyo, JP;
Jiro Fujiyasu, Tokyo, JP;
Daisuke Kaga, Tokyo, JP;
Kenji Negoro, Tokyo, JP;
Daisuke Sasuga, Tokyo, JP;
Norio Seki, Tokyo, JP;
Ken-ichi Suzuki, Tokyo, JP;
Fukushi Hirayama, Tokyo, JP;
Jiro Fujiyasu, Tokyo, JP;
Daisuke Kaga, Tokyo, JP;
Kenji Negoro, Tokyo, JP;
Daisuke Sasuga, Tokyo, JP;
Norio Seki, Tokyo, JP;
Ken-ichi Suzuki, Tokyo, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
Problem: To provide compounds which have an anticoagulation effect based on their ability to inhibit the activated blood coagulation factor X and are useful as coagulation inhibitors or agents for prevention or treatment for diseases caused by thrombi or emboli. Means for Solution: Benzene derivatives or their salts having a characteristic chemical structure with a phenol ring and a benzene ring bonding to each other via an amide bond, in which the phenol ring further bonds to a benzene ring or a heteroaryl ring via an amide bond. They have an excellent effect of inhibiting the activated blood coagulation factor X, and especially have an excellent oral activity.