The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2011

Filed:

Apr. 26, 2007
Applicants:

Shigeyuki Tanifuji, Sodegaura, JP;

Daisaku Nakamura, Sodegaura, JP;

Shinya Takasaki, Sodegaura, JP;

Inventors:

Shigeyuki Tanifuji, Sodegaura, JP;

Daisaku Nakamura, Sodegaura, JP;

Shinya Takasaki, Sodegaura, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/00 (2006.01); C07D 471/00 (2006.01); C07D 471/02 (2006.01); C07D 491/02 (2006.01); C07D 498/02 (2006.01); C07D 513/02 (2006.01); C07D 515/02 (2006.01); C07D 257/08 (2006.01); C07D 257/12 (2006.01); C07F 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a compound which has affinity with amyloid, shows sufficiently rapid clearance from normal tissues and is suppressed in toxicity such as mutagenicity, and also relates to a low-toxic diagnostic agent for Alzheimer's disease containing the compound. The compound is represented by the following formula (1) or a salt thereof: wherein A, A, Aand Aindependently represent a carbon or a nitrogen, andRis a group represented by the following formula: wherein Ris a radioactive halogen substituent; m is an integer of 0 to 4; and n is an integer of 0 or 1, provided that at least one of A, A, Aand Arepresents a carbon, and Rbinds to a carbon represented by A, A, Aor A.


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