The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2011
Filed:
Dec. 29, 2005
Rama Mukherjee, Uttar Pradesh, IN;
Sanjay Kumar Srivastava, Uttar Pradesh, IN;
Mohammad Jamshed Ahmed Siddiqui, Uttar Pradesh, IN;
Manu Jaggi, Uttar Pradesh, IN;
Anu T. Singh, Uttar Pradesh, IN;
Anand Vardhan, Uttar Pradesh, IN;
Manoj Kumar Singh, Uttar Pradesh, IN;
Praveen Rajendran, Uttar Pradesh, IN;
Hemant Kumar Jajoo, Uttar Pradesh, IN;
Anand C. Burman, Uttar Pradesh, IN;
Vivek Kumar, Uttar Pradesh, IN;
Nidhi Rani, Uttar Pradesh, IN;
Shiv Kumar Agarwal, Uttar Pradesh, IN;
Rama Mukherjee, Uttar Pradesh, IN;
Sanjay Kumar Srivastava, Uttar Pradesh, IN;
Mohammad Jamshed Ahmed Siddiqui, Uttar Pradesh, IN;
Manu Jaggi, Uttar Pradesh, IN;
Anu T. Singh, Uttar Pradesh, IN;
Anand Vardhan, Uttar Pradesh, IN;
Manoj Kumar Singh, Uttar Pradesh, IN;
Praveen Rajendran, Uttar Pradesh, IN;
Hemant Kumar Jajoo, Uttar Pradesh, IN;
Anand C. Burman, Uttar Pradesh, IN;
Vivek Kumar, Uttar Pradesh, IN;
Nidhi Rani, Uttar Pradesh, IN;
Shiv Kumar Agarwal, Uttar Pradesh, IN;
Dabur Pharma Limited, New Delhi, IN;
Abstract
The invention relates to novel betulinic acid derivatives of formula (I), wherein R is C(═CH)CHor CH(CH); Rtogether with the adjacent carbonyl group forms a carboxylic acid, carboxylic acid ester or amide or substituted amide; Ror Rare hydrogen or aryl with the proviso that both are not independently hydrogen or alkyl or Rand Rare combined together to form an aryl ring optionally substituted with a group X, wherein X is selected from halogen, alkyl, cyano, nitro, alkoxy, amino or substituted amine; Y is N or O; and Ris zero when Y is O, and Ris hydrogen, alkyl or aryl alkyl when Y is N, useful for inhibition of tumor cancer cells.