The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2011
Filed:
Oct. 31, 2002
Maria Lia Palomba, New York, NY (US);
Alan Houghton, New York, NY (US);
Jedd Wolchok, New York, NY (US);
David A. Scheinberg, New York, NY (US);
Wendy K. Roberts, New York, NY (US);
Maria Lia Palomba, New York, NY (US);
Alan Houghton, New York, NY (US);
Jedd Wolchok, New York, NY (US);
David A. Scheinberg, New York, NY (US);
Wendy K. Roberts, New York, NY (US);
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Abstract
Tolerance of the immune system for endogenous CD20 can be overcome and an immune response stimulated by administration of xenogeneic or xenoexpressed CD20 antigen. For example, mouse CD20, or antigenically-effective portions thereof, can be used to stimulate an immune response to the corresponding differentiation antigen in a human subject. Administration of xenogeneic antigens in accordance with the invention results in an effective immunity against CD20 expressed by the cancer in the treated individual, thus providing a therapeutic approach to the treatment of lymphomas and leukemia expressing CD20.