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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8017607 B1

PDFFull Text
Expired
Date of Patent:
Sep. 13, 2011

Filed:

Oct. 06, 2010

N-substituted-pyrrolidines as inhibitors of mdm2-p-53 interactions

Applicants:

David Joseph Bartkovitz, Nutley, NJ (US);

Xin-jie Chu, Livingston, NJ (US);

Jin-jun Liu, Warren Township, NJ (US);

Tina Morgan Ross, Royersford, PA (US);

Zhuming Zhang, Hillsborough, NJ (US);

Inventors:

David Joseph Bartkovitz, Nutley, NJ (US);

Xin-Jie Chu, Livingston, NJ (US);

Jin-Jun Liu, Warren Township, NJ (US);

Tina Morgan Ross, Royersford, PA (US);

Zhuming Zhang, Hillsborough, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:

George W. Johnston

Patricia S. Rocha-Tramaloni

Primary Examiner:

Sun Jae Loewe

Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/402 (2006.01); A61K 31/4155 (2006.01); A61K 31/496 (2006.01); A61K 31/454 (2006.01); A61K 31/4025 (2006.01); A61K 31/4439 (2006.01); C07D 207/16 (2006.01); C07D 403/12 (2006.01); C07D 403/06 (2006.01); C07D 401/12 (2006.01); C07D 413/14 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided compounds of the formula wherein X, Y, R, R, R, R, R, and Rare as described hereinand enantiomers and pharmaceutically acceptable salts and esters thereof which are useful as anticancer agents.

Find Patent Forward Citations

Bartkovitz, David. (2011). N-substituted-pyrrolidines as inhibitors of mdm2-p-53 interactions (U.S. Patent No. 8017607). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8017607

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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