The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2011

Filed:

Sep. 21, 2010
Applicants:

Daniela Alberati, Zofingen, CH;

Rubén Alvarez Sánchez, Rosenau, FR;

Konrad Bleicher, Freiburg, DE;

Alexander Flohr, Loerrach, DE;

Katrin Groebke Zbinden, Liestal, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach BL, CH;

Jens-uwe Peters, Grenzach-Wyhlen, DE;

Markus Rudolph, Basel, CH;

Inventors:

Daniela Alberati, Zofingen, CH;

Rubén Alvarez Sánchez, Rosenau, FR;

Konrad Bleicher, Freiburg, DE;

Alexander Flohr, Loerrach, DE;

Katrin Groebke Zbinden, Liestal, CH;

Matthias Koerner, Grenzach-Wyhlen, DE;

Bernd Kuhn, Reinach BL, CH;

Jens-Uwe Peters, Grenzach-Wyhlen, DE;

Markus Rudolph, Basel, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/44 (2006.01); A01N 43/42 (2006.01); C07D 491/02 (2006.01); C07D 498/02 (2006.01); C07D 413/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is concerned with novel imidazopyridine derivatives of formula (I) wherein R, R, R, R, Rand A are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of various diseases, including central nervous system disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.


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