The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2011
Filed:
May. 10, 2005
Jean Martinez, Caux, FR;
Pascal Verdie, Saint Mathieu de Treviers, FR;
Pascaline Dubs, Montpellier, FR;
Anne-marie Pinel, Toulouse, FR;
Gilles Subra, Juvignac, FR;
Jean Martinez, Caux, FR;
Pascal Verdie, Saint Mathieu de Treviers, FR;
Pascaline Dubs, Montpellier, FR;
Anne-Marie Pinel, Toulouse, FR;
Gilles Subra, Juvignac, FR;
Centre National de la Recherche Scientifique (CNRS), Paris, FR;
Institut Europeen de Biologie Cellulaire, Ramonville St. Ange, FR;
Universite de Montpellier I, Montpellier, FR;
Universite Montpellier II, Montpellier, FR;
Abstract
The invention relates to a tripeptide conjugate having general formula I, A-AA1-AA2-AA3-NH, wherein A represents the radical corresponding to a monocarboxylic acid with general formula II, HOOC—R, in which: R represents a linear or branched aliphatic radical at C-C, which is optionally substituted by a hydroxyl group and which can comprise one or more unsaturations, preferably between 1 and 6 unsaturations, lipoic acid or the reduced form thereof, dihydrolipoic acid, N-lipoyllysine, or phenylbutyric acid; and AA1, AA2 and AA3, which may be identical or different, represent independently of each other an amino acid selected from His, Phe, Ala, Arg, Lys, Orn, Trp, Nap, Tpi and Tic, on the condition that at least one of AA1, AA2 or AA3 represent Phe, preferably Dphe in the form of enantiomers or diastereoisomers and mixtures thereof, including racemic mixtures.