The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2011
Filed:
Jun. 17, 2008
Darren H. Wakefield, Fitchburg, WI (US);
David B. Rozema, Madison, WI (US);
Sean D. Monahan, Madison, WI (US);
Lori Higgs, Madison, WI (US);
Jon A. Wolff, Madison, WI (US);
James E. Hagstrom, Middleton, WI (US);
Darren H. Wakefield, Fitchburg, WI (US);
David B. Rozema, Madison, WI (US);
Sean D. Monahan, Madison, WI (US);
Lori Higgs, Madison, WI (US);
Jon A. Wolff, Madison, WI (US);
James E. Hagstrom, Middleton, WI (US);
Roche Madison Inc., Madison, WI (US);
Abstract
The present invention is directed to membrane active polymers useful for cellular delivery of compounds. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.