The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2011

Filed:

Aug. 19, 2009
Applicants:

Fabio Eduardo Silva E Souza, Mississauga, CA;

Ming Pan, Mississauga, CA;

Kathleen Da Silva Turcot, Toronto, CA;

Inventors:

Fabio Eduardo Silva e Souza, Mississauga, CA;

Ming Pan, Mississauga, CA;

Kathleen Da Silva Turcot, Toronto, CA;

Assignee:

Alphora Research Inc., Mississauga, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 401/00 (2006.01); C07C 35/21 (2006.01);
U.S. Cl.
CPC ...
Abstract

Paricalcitol, a synthetic vitamin D analog, is purified to a purity greater than 99.7% by crystallization from solution in isopropyl acetate solvent, followed by filtration and vacuum drying. Isopropyl acetate appears to be unique among commonly available and pharmaceutically acceptable solvents in its ability to precipitate paricalcitol in this high purity, essentially free of isomers thereof. In addition, paricalcitol of purity of at least 99.9% has been shown to have exceptional storage stability.


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