The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2011
Filed:
Nov. 23, 2005
Applicants:
Bruno Gabetta, Milan, IT;
Enrico Mercalli, Milan, IT;
Inventors:
Bruno Gabetta, Milan, IT;
Enrico Mercalli, Milan, IT;
Assignee:
Indena S.p.A., Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the purification of galanthamine (I) comprising precipitation of galanthamine hydrobromide from a mixture of alkaloids obtained from a plant of the Amaryllidaceae family containing galanthamine, treatment of the hydrobromide with alkali, extraction and crystallization of galanthamine with a solvent of general formula (II), in which Ris hydrogen or methyl and Ris selected from n-butyl, isobutyl, sec-butyl and t-butyl. The resulting pure galanthamine can be conveniently used for the preparation of galanthamine hydrobromide.