The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2011

Filed:

Jan. 23, 2003
Applicants:

Shrirang Netke, San Bruno, CA (US);

Aleksandra Niedzwiecki, San Jose, CA (US);

Matthias Rath, Bocholtz, NL;

Inventors:

Shrirang Netke, San Bruno, CA (US);

Aleksandra Niedzwiecki, San Jose, CA (US);

Matthias Rath, Bocholtz, NL;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to synthetic oligopeptides that exhibit inhibitory activity towards cancer invasion and metastasis. The peptides of the invention comprise PRKPKWDK (SEQ ID:2) peptide corresponding to amino acids of 85 to 92 of the matrix metalloproteinase (MMP-2), and fragments, analogs and homologs. The invention also relates to the uses of such peptides as inhibitory of human cancer invasion and metastasis and further to their therapeutic use in preventing and treating other pathological conditions related to the degradation of extracellular matrix by MMPs.


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