The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8012706 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 06, 2011

Filed:

May. 03, 2005
Applicants:

Jean-christophe Barale, Paris, FR;

Pierrick Uzureau, Wepion, BE;

Catherine Braun-breton, Montpellier, FR;

Inventors:

Jean-Christophe Barale, Paris, FR;

Pierrick Uzureau, Wepion, BE;

Catherine Braun-Breton, Montpellier, FR;

Assignee:

Institut Pasteur, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for regulating the serine protease of. Recombinant DNA constructs which express theserine protease, especially those comprising a sub2 3'UTR and coding segment which express a SUB2 a serine protease. Recombinantcontaining such constructs and exhibiting increased virulence. Methods for detecting virulentstrains by detecting the presence or amount of sub2 3′UTR sequences, sub2 mRNA or cDNA, SUB2 polypeptide expression, or otherproteins, such as AMA1 or MSP1, which have been post-translationally modified by SUB2.


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