The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2011
Filed:
Mar. 01, 2007
Willy Deleersnijder, Vaalbeek, BE;
Yasmin Karimi-nejad, Hannover, DE;
Michael Weske, Burgdorf, DE;
Dieter Ziegler, Hemmingen, DE;
Willy Deleersnijder, Vaalbeek, BE;
Yasmin Karimi-Nejad, Hannover, DE;
Michael Weske, Burgdorf, DE;
Dieter Ziegler, Hemmingen, DE;
Abbott Healthcare Products B.V., CP Weesp, NL;
Abstract
Polypeptides which are related to the neprilysin enzyme family and have zinc metalloprotease activities and are referred to as IGS5, polynucleotides encoding such polypeptides, vectors containing such polynucleotides, host cells containing such vectors, processes for producing such polypeptides and/or polynucleotides, screening methods for identifying compounds which stimulate or inhibit IGS5 polypeptides and/or polynucleotides, and the use of such polypeptides and/or polynucleotides in therapy of various dysfunctions, disorders or diseases, particularly cardiovascular diseases, metabolic diseases such as diabetes mellitus type II, and neurodegenerative disorders, such as Parkinson's Disease.