The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2011

Filed:

Jan. 09, 2006
Applicants:

Hyunsuk Shim, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

James P. Snyder, Atlanta, GA (US);

Weiqiang Zhan, Decatur, GA (US);

Zhongxing Liang, Tucker, GA (US);

Inventors:

Hyunsuk Shim, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

James P. Snyder, Atlanta, GA (US);

Weiqiang Zhan, Decatur, GA (US);

Zhongxing Liang, Tucker, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/505 (2006.01); C07D 239/02 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 487/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor, and in particular to inhibit viral entry of certain viruses. Certain compounds in particular can reduce entry of immunodeficiency virus (HIV) into a cell while not reducing the capacity of stem cells to proliferate, and therefore can be useful for long term treatment regimes. The compounds are useful in particular in the treatment or prevention of HIV infections.


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