The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2011
Filed:
Nov. 21, 2003
Applicants:
Arthur M. Krieg, Wellesley, MA (US);
Alfred D. Steinberg, Potomac, MD (US);
Dennis Klinman, Potomac, MD (US);
Inventors:
Arthur M. Krieg, Wellesley, MA (US);
Alfred D. Steinberg, Potomac, MD (US);
Dennis Klinman, Potomac, MD (US);
Assignees:
University of Iowa Foundation, Iowa City, IA (US);
The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);
Coley Pharmaceutical Group, Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.