The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2011
Filed:
Oct. 11, 2007
Elmar Weinhold, Aachen, DE;
Christian Dalhoff, Berlin, DE;
Saulius Klimasauskas, Vilnius, LT;
Grazvydas Lukinavicius, Vilnius, LT;
Elmar Weinhold, Aachen, DE;
Christian Dalhoff, Berlin, DE;
Saulius Klimasauskas, Vilnius, LT;
Grazvydas Lukinavicius, Vilnius, LT;
RWTH Aachen, Aachen, DE;
Abstract
S-Adenosyl-L-methionine analogs of formula (I): are disclosed wherein R comprises a carbon-carbon double bond, carbon-sulfur double bond, carbon-nitrogen double bond, -a carbon-carbon triple bond, carbon-nitrogen triple bond or an aromatic carbocyclic or heterocyclic system in β-position to the sulfonium center, Xis an organic or inorganic anion carrying one or more negative charges, Z is —CRR—, —O—, —S— or —NR— and R, Rand Rare independently selected from H, D and C—C alkyl; as well as complexes with a methyltransferase, pharmaceutical compositions, methods for modifying a biomolecule, and methods for detecting sequences specific methylation of biomolecules.