The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2011
Filed:
Oct. 08, 2003
Alicia Santos Savio, Ciudad de la Habana, CU;
Ricardo Silva Rodriguez, Ciudad de la Habana, CU;
Yanelis Morera Diaz, Ciudad de la Habana, CU;
Armando Alexei Rodriquez Alfonso, Ciudada de la Habana, CU;
Jose Rafael Martinez Castillo, Ciudad de la Habana, CU;
Haydee Geronimo Perez, Ciudad de la Habana, CU;
Alejandro Moro Soria, Ciudad de la Habana, CU;
Silvio Ernesto Perea Rodriguez, Ciudad de la Habana, CU;
Alicia Santos Savio, Ciudad de la Habana, CU;
Ricardo Silva Rodriguez, Ciudad de la Habana, CU;
Yanelis Morera Diaz, Ciudad de la Habana, CU;
Armando Alexei Rodriquez Alfonso, Ciudada de la Habana, CU;
Jose Rafael Martinez Castillo, Ciudad de la Habana, CU;
Haydee Geronimo Perez, Ciudad de la Habana, CU;
Alejandro Moro Soria, Ciudad de la Habana, CU;
Silvio Ernesto Perea Rodriguez, Ciudad de la Habana, CU;
Centro de Ingenieria Genetica y Biotecnologia, Cuidad de la Habana, CU;
Abstract
Vaccine composition containing IL-15 for active immunization to treatment diseases related to over-expression of this cytokine. The technical aim pursued in this invention is to inhibit IL-15 activity through development of a therapeutic vaccine which elicits IL-15 neutralizing antibodies in the immunized host. IL-15 can be presented in this vaccine composition either alone or coupled to a carrier such as the P64k protein with a vaccine adjuvant such as Aluminum hydroxide. Besides, this invention is related to the use of this vaccine for treatment of Rheumatoid arthritis and other IL-15 over-expressing related diseases, and leukemia, where this cytokine acts as a growth factor.