The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2011

Filed:

Jun. 16, 2009
Applicants:

Jianping Cai, West Caldwell, NJ (US);

Shaoqing Chen, Bridgewater, NJ (US);

Xin-jie Chu, Livingston, NJ (US);

Kin-chun Luk, North Caldwell, NJ (US);

Steven Gregory Mischke, Florham Park, NJ (US);

Hongmao Sun, Ramsey, NJ (US);

Peter Michael Wovkulich, Nutley, NJ (US);

Inventors:

Jianping Cai, West Caldwell, NJ (US);

Shaoqing Chen, Bridgewater, NJ (US);

Xin-Jie Chu, Livingston, NJ (US);

Kin-Chun Luk, North Caldwell, NJ (US);

Steven Gregory Mischke, Florham Park, NJ (US);

Hongmao Sun, Ramsey, NJ (US);

Peter Michael Wovkulich, Nutley, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides PLK1 inhibitor compounds of formula I: useful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.


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