The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2011

Filed:

Dec. 12, 2008
Applicants:

Laura S. Schmidt, Mt. Airy, MD (US);

Michelle Warren, New Market, MD (US);

Jorge R. Toro, Washington, DC (US);

Berton Zbar, Garrett Park, MD (US);

Michael L. Nickerson, Shepherdston, WV (US);

W. Marston Linehan, North Bethesda, MD (US);

Maria L. Turner, Washington, DC (US);

Inventors:

Laura S. Schmidt, Mt. Airy, MD (US);

Michelle Warren, New Market, MD (US);

Jorge R. Toro, Washington, DC (US);

Berton Zbar, Garrett Park, MD (US);

Michael L. Nickerson, Shepherdston, WV (US);

W. Marston Linehan, North Bethesda, MD (US);

Maria L. Turner, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and antibodies that specifically bind to the BHD protein (folliculin). In addition, the present disclosure relates to methods of diagnosing BHD disease and related conditions, such as spontaneous pneumothorax and kidney cancer, by detection of altered expression of folliculin using folliculin-specific antibodies.


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